This course will introduce students to bioinformatics and the analysis of next-generation sequencing (NGS) data. Bioinformatics is the application of computational techniques to the study of biological data, and NGS technology has revolutionized the way we study genetics and genomics. Through a combination of lectures and hands-on laboratory exercises, students will learn the principles of bioinformatics and NGS data analysis and gain practical experience with the tools and methods used in the field. Topics will include data QC, sequencing reads mapping, variant calling and annotation. By the end of the course, students will have the skills to analyze and interpret NGS data for their own research projects.

Prerequisites: Participants are expected to have basic knowledge of biology. Previous experience in programming and knowledge of the UNIX/Linux environment will be beneficial but is not necessary.

Syllabus: Link to syllabus

Date:  27 August 2024 - 1 October 2024

Time: Tue Thu 2:30 PM - 4:00 PM

Instructor: Pavel Dobrynin, Ph.D.

Teaching Assistant: TBD

Location: Join Microsoft Teams

Attendance Requirement: 

Good standing on Attendance grade (>50%) would be required to see new course materials and participate in research projects as the course proceeds. Also, for students interested in getting a badge or certificate for completing this course, an attendance grade of at least 12 hours of the class meeting sessions is required, to be qualified for passing the course and getting the badge.

Textbook: None Required

Lecture notes would be provided through the course website.

Evaluation (tentative): Attendance: 20%, Workshop performance: 30%, Research project: 50%

Fees: The course is FREE to the UH System community ( students, staff, and faculty)

Non-UH Affiliate Registration Fee: $250.00

UH Alumni Registration Fee: $250.00

For more information contact us at: 

** Non-UH affiliates and alumni registering for the HPE DSI classes MUST:

(1) complete the payment of the course fees ($250.00 per course) at least three(3) weeks before course commencement.

(2) inform HPE DSI of their interest in taking the course at least three(3) weeks before the course start date. This will allow adequate time for processing of your course access credentials before the first-class meeting.

If you need to cancel a course for any reason, e-mail us at

** The following refund schedule applies:

More than three weeks before the start date: A cancellation fee of 10% of the total workshop cost applies.

Less than three weeks before the start date: 15% cancellation fee applies.

Less than one week before the start date: 25% cancellation fee applies.

48 hours or less before class start: No refund is available.

All deposits and payments made are non-transferable. The HPE DSI cannot provide refunds, transfer payments, or offer makeup sessions for classes a student might miss, for any reason. If the HPE DSI has to cancel a workshop, you will receive a full refund.

Copyright protection: The course materials and online lecture videos posted on Blackboard/Moodle are only meant to be used within this course and should not be distributed.

The University of Houston Academic Honesty Policy applies:

Students in need of counseling: Counseling and Psychological Services (CAPS) can help students who are having difficulties managing stress, adjusting to the demands of a professional program, or feeling sad and hopeless. You can reach CAPS ( by calling 713-743-5454 during and after business hours for routine appointments or if you or someone you know is in crisis. No appointment is necessary for the “Let's Talk” program, a drop-in consultation service at convenient locations and hours around campus.